Week 1 of the 2025 Fantasy Football season has finally arrived, and all managers should be working on their starting lineups. Picking the right tight ends can sometimes be the difference between winning and losing.
Here are some of the best ones to target and fade for the opening week of this season.
Fantasy Football Week 1 TEs Start 'Em Picks


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Week 1 is always one of the most challenging weeks to navigate in any Fantasy Football season. Many unknowns surround players, including what type of role they will play in their offensive systems. Those with unchanged situations from the season before are often the safest picks in Week 1.
George Kittle is an ideal example of this for tight ends in 2025, and he could get an additional boost to his already elite fantasy value to open the year. He has finished among the top five tight ends in Fantasy Football in each of the past four years and has consistency with the coach and quarterback situation.
The San Francisco 49ers moved on from Deebo Samuel during the offseason, and Brandon Aiyuk is currently on the injured list. Jauan Jennings' availability is also in question, so Kittle is lined up for a massive workload this week. He is always one of the best options for the position, but he appears to be a home run pick against the Seattle Seahawks.
Must Starts
- George Kittle
- Brock Bowers
- Trey McBride
- Travis Kelce
- Sam LaPorta
- Mark Andrews
DFS Picks
- Jake Ferguson
- Tucker Kraft
- David Njoku
Fantasy Football Week 1 TEs Sit 'Em Picks

Identifying which tight ends to fade is just as important as deciding which ones to target in a given week. This can often be the result of going through significant changes during the offseason, such as switching teams, adapting to a new offensive system, or facing increased competition for targets.
Jonnu Smith is a typical example of this in Week 1 after switching teams to the Pittsburgh Steelers. He broke out for a career-best TE4 finish with the Miami Dolphins last year, but his path to a consistent workload is questionable this year. He will compete with Pat Freiermuth for playing time, so it's best to wait and see before adding him to lineups.
Must Sits
- Jonnu Smith
- Mike Gesicki
- Cole Kmet
- Dalton Schultz
- Pat Freiermuth
- Darren Waller
DFS Fades
- TJ Hockenson
- Tyler Higbee
- Hunter Henry
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