2025 Fantasy Football mock draft 12-team PPR: Justin Herbert, Ladd McConkey stack league-winner upside

Managers should always be as prepared as possible for fantasy football drafts in order to give themselves the best chance at winning a championship. Participating in mock drafts is one of the most useful ways to come up with a draft strategy based on pick number.

Here's an example with the last pick in a 12-team PPR league.

Fantasy Football mock draft with 12th pick

Mock Draft

Round 1, Pick 12: Nico Collins, Texans WR

Nico Collins is one of the most reliable fantasy football wide receivers to pick late in the first round of drafts this year. He should be in line for a massive workload as the Texans' top target.

Round 2, Pick 1: Ashton Jeanty, Raiders RB

Ashton Jeanty is the highest-ranked rookie in just about all fantasy football rankings for this year. He is expected to serve as the workhorse for the Raiders, so like Bijan Robinson recently, he could immediately become a breakout star.

Round 3, Pick 12: Ladd McConkey, Chargers WR

Ladd McConkey finished as the overall WR12 in his rookie season last year, so he could be a steal at this point in the draft. Sportskeeda's Who Should I Draft tool recommends the Chargers' emerging star over many other similar options.

Round 4, Pick 1: Jaxon Smith-Njigba, Seahawks WR

Jaxon Smith-Njigba could be one of the biggest sleeper picks this year with DK Metcalf departing the Seahawks. He will compete with an aging Cooper Kupp for targets, but JSN's upside gives him top 10 potential.

Round 5, Pick 12: Isiah Pacheco, Chiefs RB

Isiah Pacheco appeared well on his way to having a career year with the Chiefs last season before being derailed by an injury. He is an ideal bone back candidate in an elite offensive system.

Round 6, Pick 1: Justin Herbert, Chargers QB

Stacking quarterbacks with their top wide receiver has long been a valuable fantasy football draft strategy in the right spots. Doing so with Justin Herbert and Ladd McConkey this year could be game-changing, especially in relation to their favorable ADP currently.

Round 7, Pick 12: Calvin Ridley, Titans WR

Calvin Ridley is one of the biggest potential sleeper picks this year after getting a new quarterback with the Titans. If rookie Cam Ward lives up to his potential, Ridley should be the biggest beneficiary.

Round 8, Pick 1: Mark Andrews, Ravens TE

Mark Andrews has been as consistently reliable as any fantasy football tight end in recent years. He could get an additional boost to his value in the early stages of the 2025 season with Isaiah Likely in danger of missing time for the Ravens.

Round 9, Pick 12: Dylan Sampson, Browns RB

Dylan Sampson was the second running back selected by the Browns in the 2025 NFL draft. With Quinshon Judkins still unsigned amid issues off the field, Sampson may get an earlier opportunity at being a featured back than initially expected.

Round 10, Pick 1: Khalil Shakir, Bills WR

Khalil Shakir remains the top wide receiver for the Bills this year after they declined to add a significant option during the offseason. Being the top target for defending NFL MVP Josh Allen brings a ton of upside.