As Bundesliga action resumes over the weekend after a three-week break, RB Leipzig host Mainz at Red Bull Arena on Saturday in their first game of 2022.In this mid-table clash, the hosts find themselves in 10th position in the league standings with 22 points, one place and two points behind Mainz. In their last fixture ahead of the winter break, they were defeated 2-0 at home by Arminia Bielefeld.Mainz also suffered a defeat in their previous outing as they faced a 1-0 defeat at Eintracht Frankfurt in December.Bundesliga English@Bundesliga_ENWE. ARE. BACK. 🤩✍️ __________ is going to be the of the #Bundesliga Rückrunde 3:00 AM · Jan 7, 202215125WE. ARE. BACK. 🤩✍️ __________ is going to be the ⭐️ of the #Bundesliga Rückrunde 👇 https://t.co/4T45ZEuS0tRB Leipzig vs Mainz Head-to-HeadThe two sides have locked horns 11 times since 2016, with all of these meetings coming in the Bundesliga. Leipzig have been the better side in this fixture and lead 6-3 in wins while two games have ended in a draw.Mainz's all three wins in the fixture have come in their home games and two of them came in 2021. They last met in the opening fixture of the 2021-22 campaign at MEWA Arena with Moussa Niakhaté's early goal giving Die Nullfünfer a 1-0 win.RB Leipzig form guide (all competitions): L-D-W-W-LMainz form guide (Bundesliga): L-W-L-W-LRB Leipzig vs Mainz Team NewsRB LeipzigEmil Forsberg will be a key absentee for the hosts as he is ruled out with a thigh injury and is expected back in February. Here are the rest of the absentees for Die Roten Bullen:Dani Olmo - Hamstring injury & COVID-19Konrad Laimer - Ankle injuryMarcel Halstenberg - Knee injuryNordi Mukiele - COVID-19Benjamin Henrichs - COVID-19Amadou Haidara - International duty (AFCON - Mali)Ilaix Moriba - International duty (AFCON - Guinea)RB Leipzig English@RBLeipzig_EN Team news ahead of #RBLM05: @andrevsilva19 trained again after returning yesterday @c_nk97 returned to training today after yesterday's negative test @yussufyurary was able to train well #WeAreLeipzig9:21 AM · Jan 6, 2022514ℹ️ Team news ahead of #RBLM05:✅ @andrevsilva19 trained again after returning yesterday✅ @c_nk97 returned to training today after yesterday's negative test✅ @yussufyurary was able to train well🔴⚪ #WeAreLeipzig https://t.co/WTvzjTAkaiInjured: Marcel Halstenberg, Emil Forsberg, Konrad LaimerUnavailable: Dani Olmo (COVID-19), Nordi Mukiele (COVID-19), Benjamin Henrichs (COVID-19), Amadou Haidara (International duty - AFCON), Ilaix Moriba (International duty - AFCON)Suspended: NoneMainz Adam Szalai has resumed training but is not expected back into the starting XI just yet. Here are the rest of the absentees for the visiting side:Dominik Kohr - Muscle injuryJerry St. Juste - Shoulder injuryMoussa Niakhate - COVID-19Injured: Adam Szalai, Dominik Kohr, Jerry St. JusteDoubtful: NoneSuspended: NoneUnavailable: Moussa Niakhate (COVID-19)RB Leipzig vs Mainz Predicted XIRB Leipzig Predicted XI (3-5-2): Peter Gulacsi; Lukas Klostermann, Josko Gvardiol, Willi Orbán; Angelino, Tyler Adams, Kevin Kampl, Hugo Novoa, Dominik Szoboszlai; Andre Silva, Christopher NkunkuMainz Predicted XI (3-5-1-1): Robin Zentner; David Nemeth, Alexander Hack, Stefan Bell; Aaron Caricol, Jae-sung Lee, Anton Stach, Leandro Barreiro, Silvan Widmer; Marcus Ingvartsen; Jonathan BurkhardtRB Leipzig vs Mainz PredictionAll seven of Mainz's losses in the Bundesliga this term have come on their travels while Leipzig have faced three losses at home. Leipzig have scored five goals more than the visitors and conceded five more as well.Given Mainz's poor record in their travels, a narrow loss for them here looks like the most likely outcome from the game.Prediction: RB Leipzig 2-1 Mainz.