Cambridge United will host Luton Town at the Abbey Stadium in the fourth round of the FA Cup on Saturday.The home side secured their spot at this stage by virtue of their shock 1-0 away victory over Premier League side Newcastle United in January. Joe Ironside scored in the 56th minute to help the League One outfit secure a memorable cup win.The Hatters comfortably dispatched Harrogate 4-0 on home turf to progress. Four different men got on the scoresheet for the Championship side.Luton Town FC@LutonTown Match preview Back in @EmiratesFACup action this weekend and searching for a place in the fifth round.#COYH12:30 PM · Feb 3, 2022602📂 Match preview 👇Back in @EmiratesFACup action this weekend and searching for a place in the fifth round.#COYHThe Hatters come into the game on the back of a 1-0 away victory over Swansea City in the EFL Championship. Harry Cornick stepped off the bench to help his side leave Wales with all three points.Cambridge United fell to a 2-0 defeat away to Bolton Wanderers in League One. Amadou Bakayoko and Oladapo Afolayan scored in either half to help their side secure the win.Cambridge United vs Luton Town Head-to-HeadThis will be the 27th meeting between the two sides. The Hatters have been the historically superior team with 11 wins to their name.Cambridge United were victorious on six occasions while nine matches in the past ended in a share of the spoils.Their most recent meeting came in a League Two fixture in March 2018 when goals from James Collins and Jabo Ibehre saw both sides share the spoils in a 1-1 draw.Cambridge United form guide (all competitions): L-D-L-W-WLuton Town form guide (all competitions): W-D-W-L-WCambridge United vs Luton Town Team NewsCambridge United Jack Iredale was substituted in the first half against Bolton due to an ankle injury and might not be fit in time for this game.Injury: Jack IredaleSuspension: NoneCambridge United FC@CambridgeUtdFCHear the thoughts of both Head Coach Mark Bonner and George Williams ahead of Saturday's clash with @LutonTown. #CamUTD3:00 AM · Feb 3, 202218Hear the thoughts of both Head Coach Mark Bonner and George Williams ahead of Saturday's clash with @LutonTown. 💬 #CamUTDLuton TownThere are no known injury or suspension worries for the club.Injuries: NoneSuspension: NoneCambridge United vs Luton Town Predicted XICambridge United Predicted XI (4-2-3-1): Dimitar Mitov (GK); Harrison Dunk, Sam Sherring, Jubril Okedina, George Williams; Ben Worman, Paul Digby; James Brophy, Adam May, Harvey Knibbs; Sam SmithLuton Town Predicted XI (3-4-2-1): James Shea; Daniel Potts, Sonny Bradley, Kal Naismith; James Bree, Allan Campbell, Pelly Mpanzu, Amari'i Bell; Jordan Clark, Fred Onyedinma; Elijah AdebayoCambridge United vs Luton Town PredictionThe Hatters are favorites for the game, although the magic of the FA Cup means that an upset is not entirely out of the question. The home side have not really impressed in recent weeks but their recent victory over Newcastle United could spur them on to register another scalp.The Hatters' recent ascent in the Championship has been spurred by defensive solidity. We are backing Nathan Jones' side to secure a narrow victory in addition to a clean sheet.Prediction: Cambridge United 0-1 Luton Town