The Illinois Fighting Illini, representing the top-seed in the Midwest region, blew out the 16th-seeded Drexel Dragons in the first round and will now play the 8th-seeded Loyola Chicago Ramblers. The Fighting Illini are currently on a seven-game winning streak, dating back to February 25th. The Ramblers took down ACC champion Georgia Tech Yellow Jackets in the opening round, but their focus will be on a massive upset this Sunday.Match detailsFixture: Loyola Chicago Ramblers vs. Illinois Fighting Illini - March Madness 2021: Round of 32Date & Time: Sunday, March 21, 2021, 12:10 PM ETVenue: Bankers Life Fieldhouse, Indianapolis, Indiana_________________________________________________________________Loyola Chicago Ramblers previewLoyola Chicago Ramblers superfan "Sister Jean"The Loyola Chicago Ramblers passed their first test in March Madness 2021, securing an impressive 11-point victory over a talented Georgia Tech team. The Ramblers will now have their biggest challenge yet, upsetting the top-seeded Illinois Fighting Illini.The Ramblers averaged 71.5 points per game this season, a whopping ten points less than the Illinois offense. The Ramblers must rely on defense, experience and pure momentum if they are going to make another Sweet Sixteen appearance.Key player - Lucas WilliamsonLoyola Chicago Ramblers' senior guard Lucas Williamson brought the hot hand to Indianapolis, tallying a game-high 21 points in his team's first-round victory. Williamson averaged just 8.6 points and four rebounds per game, but tallied a season-high in the biggest game of the season.Lucas Williamson on playing Illinois: At the end of the day, this is March Madness. I'm just trying to survive and advance. Illinois is going to be a tough matchup for us. ... Ultimately, I'm just focused on whoever's in front of me, and it just happens to be Illinois.— Nick Schultz (@NickSchultz_7) March 19, 2021Lucas Williamson was part of the Ramblers' magical run to the Final Four in 2018, so he will be eager to return to the big stage. If Loyola Chicago is able to get their offense rolling early, it could be a problem for the Illinois Fighting Illini on Sunday.Loyola Chicago Ramblers predicted lineupF Aher Uguak, C Cameron Krutwig, G Keith Clemons, G Braden Norris, G Lucas Williamson_________________________________________________________________Illinois Fighting Illini previewIllinois Fighting Illini guard #11 Ayo DosunmuThe Illinois Fighting Illini are looking like a Final Four contender, carrying a 24-6 overall record into this matchup. The Fighting Illini fell just short of a Big Ten regular-season title, but took the Big Ten Tournament championship and earned themselves top-seed in the Midwest.Illinois' offense is led by star guard Ayo Dosunmu, but this is a well-balanced group with threats all over the floor. The Loyola Chicago Ramblers will need their best basketball and also some luck if they are going to shock the Illinois Fighting Illini in this second-round matchup.Key player - Kofi CockburnWhile Ayo Dosunmu will undoubtedly be a big factor, Kofi Cockburn will need to provide a strong presence in the paint to give Illinois the edge on Sunday. Cockburn tallied a game-high 18 points on 73% shooting in the Fighting Illini's first-round matchup.#illini Kofi Cockburn: When I came on my visit, I saw this program as a losing program. They lost to a really bad team when I came here. That motivated me to come here and be a part of this change.— Joey Wagner (@mrwagner25) March 13, 2021Kofi Cockburn will battle Cameron Krutwig and Aher Uguak of the Loyola Chicago Ramblers, making his contribution from the paint a huge factor. The Illinois Fighting Illini will be the favorites in this matchup, but they cannot afford to take the Ramblers lightly.Illinois Fighting Illini predicted lineupG Jacob Grandison, C Kofi Cockburn, G Trent Frazier, G Ayo Dosunmu, G Adam Miller_________________________________________________________________Loyola Chicago vs. Illinois predictionThe Loyola Chicago Ramblers will be the underdogs in this matchup, but they will have the support of many March Madness fans. The Ramblers have become a potential "Cinderella story" since their deep tournament run in 2018. The Illinois Fighting Illini will outmatch Loyola Chicago in nearly every spot on the floor, but they still need to play their game. Illinois will have the edge, but the power of momentum in the tournament is not to be understated.Where to watch Loyola Chicago vs. IllinoisThe game will be broadcast live on CBS.